Postnatal Ablation of POMC Neurons Induces an Obese Phenotype Characterized by Decreased Food Intake and Enhanced Anxiety-Like Behavior

Proopiomelanocortin (POMC) neurons in the arcuate nucleus of the hypothalamus are central components of systems regulating appetite and energy homeostasis. Here we report on the establishment of a mouse model in which the ribonuclease III ribonuclease Dicer-1 has been specifically deleted from POMC-...

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Detalhes bibliográficos
Publicado no:Mol Endocrinol
Main Authors: Greenman, Yona, Kuperman, Yael, Drori, Yonat, Asa, Sylvia L., Navon, Inbal, Forkosh, Oren, Gil, Shosh, Stern, Naftali, Chen, Alon
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2013
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5415244/
https://ncbi.nlm.nih.gov/pubmed/23676213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2012-1344
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