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Human genes for the alpha and beta chains of complement C4b-binding protein are closely linked in a head-to-tail arrangement.

C4b-binding protein (C4BP) is an important component in the regulation of the complement system and also binds the anticoagulant vitamin K-dependent protein S. These activities are performed by distinct, although structurally related, polypeptides of 70 kDa (alpha chain) and 45 kDa (beta chain), res...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Pardo-Manuel, F, Rey-Campos, J, Hillarp, A, Dahlbäck, B, Rodriguez de Cordoba, S
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54149/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2352933/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.12.4529
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