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The novel negative checkpoint regulator VISTA is expressed in gastric carcinoma and associated with PD-L1/PD-1: A future perspective for a combined gastric cancer therapy?

A combined blockade of V-domain Ig suppressor of T-cell activation (VISTA) and PD-1 is a promising new cancer treatment option, which was efficient in murine tumor models and is currently tested in first phase I studies. Here, we analyzed the VISTA expression in a large and well-characterized gastri...

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Publicado en:Oncoimmunology
Main Authors: Böger, Christine, Behrens, Hans-Michael, Krüger, Sandra, Röcken, Christoph
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5414883/
https://ncbi.nlm.nih.gov/pubmed/28507801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1293215
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