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Rules for biocatalyst and reaction engineering to implement effective, NAD(P)H-dependent, whole cell bioreductions

Access to chiral alcohols of high optical purity is today frequently provided by the enzymatic reduction of precursor ketones. However, bioreductions are complicated by the need for reducing equivalents in the form of NAD(P)H. The high price and molecular weight of NAD(P)H necessitate in situ recycl...

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Pubblicato in:Biotechnol Adv
Autori principali: Kratzer, Regina, Woodley, John M., Nidetzky, Bernd
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5414839/
https://ncbi.nlm.nih.gov/pubmed/26343336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biotechadv.2015.08.006
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