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Innate Immunity, Hemostasis and Matrix Remodeling: PTX3 as a Link

Innate immunity is evolutionarily connected with hemostasis. PTX3 is an essential fluid-phase pattern recognition molecule of the innate immune system that acts as a functional ancestor of antibodies. PTX3 by interacting with defense collagens and fibrinogens amplifies effector functions of the inna...

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Publicat a:Semin Immunol
Autors principals: Doni, Andrea, Garlanda, Cecilia, Mantovani, Alberto
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5414833/
https://ncbi.nlm.nih.gov/pubmed/27881292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.smim.2016.10.012
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