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Minireview: Challenges and Opportunities in Development of PPAR Agonists

The clinical impact of the fibrate and thiazolidinedione drugs on dyslipidemia and diabetes is driven mainly through activation of two transcription factors, peroxisome proliferator-activated receptors (PPAR)-α and PPAR-γ. However, substantial differences exist in the therapeutic and side-effect pro...

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Bibliografske podrobnosti
izdano v:Mol Endocrinol
Main Authors: Wright, Matthew B., Bortolini, Michele, Tadayyon, Moh, Bopst, Martin
Format: Artigo
Jezik:Inglês
Izdano: Endocrine Society 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5414793/
https://ncbi.nlm.nih.gov/pubmed/25148456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2013-1427
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