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Minireview: Challenges and Opportunities in Development of PPAR Agonists

The clinical impact of the fibrate and thiazolidinedione drugs on dyslipidemia and diabetes is driven mainly through activation of two transcription factors, peroxisome proliferator-activated receptors (PPAR)-α and PPAR-γ. However, substantial differences exist in the therapeutic and side-effect pro...

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Detalhes bibliográficos
Publicado no:Mol Endocrinol
Main Authors: Wright, Matthew B., Bortolini, Michele, Tadayyon, Moh, Bopst, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5414793/
https://ncbi.nlm.nih.gov/pubmed/25148456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2013-1427
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