Fetal Leydig Cells Persist as an Androgen-Independent Subpopulation in the Postnatal Testis

Two distinct types of Leydig cells emerge during the development of eutherian mammals. Fetal Leydig cells (FLCs) appear shortly after gonadal sex differentiation, and play a crucial role in masculinization of male fetuses. Meanwhile, adult Leydig cells (ALCs) emerge after birth and induce the second...

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Veröffentlicht in:Mol Endocrinol
Hauptverfasser: Shima, Yuichi, Matsuzaki, Sawako, Miyabayashi, Kanako, Otake, Hiroyuki, Baba, Takashi, Kato, Shigeaki, Huhtaniemi, Ilpo, Morohashi, Ken-ichirou
Format: Artigo
Sprache:Inglês
Veröffentlicht: Endocrine Society 2015
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5414671/
https://ncbi.nlm.nih.gov/pubmed/26402718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2015-1200
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