Broadly neutralizing antibodies with few somatic mutations and hepatitis C virus clearance

Here, we report the isolation of broadly neutralizing mAbs (bNAbs) from persons with broadly neutralizing serum who spontaneously cleared hepatitis C virus (HCV) infection. We found that bNAbs from two donors bound the same epitope and were encoded by the same germline heavy chain variable gene segm...

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Bibliografiset tiedot
Julkaisussa:JCI Insight
Päätekijät: Bailey, Justin R., Flyak, Andrew I., Cohen, Valerie J., Li, Hui, Wasilewski, Lisa N., Snider, Anna E., Wang, Shuyi, Learn, Gerald H., Kose, Nurgun, Loerinc, Leah, Lampley, Rebecca, Cox, Andrea L., Pfaff, Jennifer M., Doranz, Benjamin J., Shaw, George M., Ray, Stuart C., Crowe, James E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 2017
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5414559/
https://ncbi.nlm.nih.gov/pubmed/28469084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.92872
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