The CpG island methylator phenotype is concordant between primary colorectal carcinoma and matched distant metastases

BACKGROUND: The CpG island methylator phenotype (CIMP) in stage III colon cancer (CRC) has been associated with improved survival after treatment with adjuvant irinotecan-based chemotherapy. In this analysis, we determine whether CIMP status in the primary CRC is concordant with the CIMP status of m...

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Publicado en:Clin Epigenetics
Autores principales: Cohen, Stacey A., Yu, Ming, Baker, Kelsey, Redman, Mary, Wu, Chen, Heinzerling, Tai J., Wirtz, Ralph M., Charalambous, Elpida, Pentheroudakis, George, Kotoula, Vassiliki, Kalogeras, Konstantine T., Fountzilas, George, Grady, William M.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5414304/
https://ncbi.nlm.nih.gov/pubmed/28469732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-017-0347-1
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