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Chemical synthesis of long RNAs with terminal 5′‐phosphate groups

Long structured RNAs are useful biochemical and biological tools. They are usually prepared enzymatically, but this precludes their site‐specific modification with functional groups for chemical biology studies. One solution is to perform solid‐phase synthesis of multiple RNAs loaded with 5′‐termina...

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Publicado en:Chemistry
Main Authors: Pradère, Ugo, Halloy, François, Hall, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5413853/
https://ncbi.nlm.nih.gov/pubmed/28295757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201700514
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