Soluble Ectodomain of Neuroligin 1 Decreases Synaptic Activity by Activating Metabotropic Glutamate Receptor 2

Synaptic cell adhesion molecules represent important targets for neuronal activity-dependent proteolysis. Postsynaptic neuroligins (NLs) form trans-synaptic complexes with presynaptic neurexins (NXs). Both NXs and NLs are cleaved from the cell surface by metalloproteases in an activity-dependent man...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Gjørlund, Michelle D., Carlsen, Eva M. M., Kønig, Andreas B., Dmytrieva, Oksana, Petersen, Anders V., Jacobsen, Jacob, Berezin, Vladimir, Perrier, Jean-François, Owczarek, Sylwia
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5413576/
https://ncbi.nlm.nih.gov/pubmed/28515678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00116
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