Selegiline Ameliorates Depression-Like Behavior in Mice Lacking the CD157/BST1 Gene, a Risk Factor for Parkinson’s Disease

Parkinson’s disease (PD), a neurodegenerative disorder, is accompanied by various non-motor symptoms including depression and anxiety, which may precede the onset of motor symptoms. Selegiline is an irreversible monoamine oxidase-B (MAO-B) inhibitor, and is widely used in the treatment of PD and maj...

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Detalhes bibliográficos
Publicado no:Front Behav Neurosci
Main Authors: Kasai, Satoka, Yoshihara, Toru, Lopatina, Olga, Ishihara, Katsuhiko, Higashida, Haruhiro
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5413561/
https://ncbi.nlm.nih.gov/pubmed/28515684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnbeh.2017.00075
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