The kinase TBK1 functions in dendritic cells to regulate T cell homeostasis, autoimmunity, and antitumor immunity

Dendritic cells (DCs) are crucial for mediating immune responses but, when deregulated, also contribute to immunological disorders, such as autoimmunity. The molecular mechanism underlying the function of DCs is incompletely understood. In this study, we have identified TANK-binding kinase 1 (TBK1),...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Xiao, Yichuan, Zou, Qiang, Xie, Xiaoping, Liu, Ting, Li, Haiyan S., Jie, Zuliang, Jin, Jin, Hu, Hongbo, Manyam, Ganiraju, Zhang, Li, Cheng, Xuhong, Wang, Hui, Marie, Isabelle, Levy, David E., Watowich, Stephanie S., Sun, Shao-Cong
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2017
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Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5413337/
https://ncbi.nlm.nih.gov/pubmed/28356390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20161524
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