Neutrophil myeloperoxidase diminishes the toxic effects and mortality induced by lipopolysaccharide

Neutrophils have crucial antimicrobial functions but are also thought to contribute to tissue injury upon exposure to bacterial products, such as lipopolysaccharide (LPS). To study the role of neutrophils in LPS-induced endotoxemia, we developed a new mouse model, PMN(DTR) mice, in which injection o...

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Vydáno v:J Exp Med
Hlavní autoři: Reber, Laurent L., Gillis, Caitlin M., Starkl, Philipp, Jönsson, Friederike, Sibilano, Riccardo, Marichal, Thomas, Gaudenzio, Nicolas, Bérard, Marion, Rogalla, Stephan, Contag, Christopher H., Bruhns, Pierre, Galli, Stephen J.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2017
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5413333/
https://ncbi.nlm.nih.gov/pubmed/28385925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20161238
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