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The Epstein-Barr virus miR-BHRF1-1 targets RNF4 during productive infection to promote the accumulation of SUMO conjugates and the release of infectious virus

Post-translational modification by the Small Ubiquitin-like Modifier (SUMO) regulates a variety of cellular functions, and is hijacked by viruses to remodel the host cell during latent and productive infection. Here we have monitored the activity of the SUMO conjugation machinery in cells productive...

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Библиографические подробности
Опубликовано в: :PLoS Pathog
Главные авторы: Li, Jinlin, Callegari, Simone, Masucci, Maria G.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5413087/
https://ncbi.nlm.nih.gov/pubmed/28414785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006338
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