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Palmitic acid is a toll-like receptor 4 ligand that induces human dendritic cell secretion of IL-1β

Palmitic acid (PA) and other saturated fatty acids are known to stimulate pro-inflammatory responses in human immune cells via Toll-like receptor 4 (TLR4). However, the molecular mechanism responsible for fatty acid stimulation of TLR4 remains unknown. Here, we demonstrate that PA functions as a lig...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:PLoS One
Main Authors: Nicholas, Dequina A., Zhang, Kangling, Hung, Christopher, Glasgow, Shane, Aruni, Aruni Wilson, Unternaehrer, Juli, Payne, Kimberly J., Langridge, William H. R., De Leon, Marino
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2017
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5413048/
https://ncbi.nlm.nih.gov/pubmed/28463985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0176793
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