Mechanistic insights into the more potent effect of KP-54 compared to KP-10 in vivo

Kisspeptins regulate the mammalian reproductive axis by stimulating release of gonadotrophin releasing hormone (GnRH). Different length kisspeptins (KP) are found of 54, 14, 13 or 10 amino-acids which share a common C-terminal 10-amino acid sequence. KP-54 and KP-10 have been widely used to stimulat...

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Udgivet i:PLoS One
Main Authors: d'Anglemont de Tassigny, Xavier, Jayasena, Channa, Murphy, Kevin G., Dhillo, Waljit S., Colledge, William H.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5413024/
https://ncbi.nlm.nih.gov/pubmed/28464043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0176821
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