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Drug interaction between tacrolimus and nilotinib in a patient with chronic myeloid leukemia after renal transplant

Nilotinib, a BCR‐ABL tyrosine kinase inhibitor, is a known inhibitor of CYP3A4 and could increase the concentration of drugs metabolized by CYP3A4. An immunosuppressive drug for nilotinib‐treated patients following transplant should be administered with careful pharmacokinetic monitoring because of...

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Publicado en:Clin Case Rep
Autores principales: Onaka, Takashi, Takahashi, Naoto, Miura, Masatomo, Yonezawa, Akihito
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5412900/
https://ncbi.nlm.nih.gov/pubmed/28469859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ccr3.900
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