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NG-methyl-L-arginine causes endothelium-dependent contraction and inhibition of cyclic GMP formation in artery and vein.

The objective of this study was to determine whether the vascular smooth muscle contractile effect of NG-methyl-L-arginine (NMA) is endothelium dependent and attributed to a decline in smooth muscle levels of cyclic GMP. Vascular smooth muscle levels of cyclic GMP are severalfold greater in endothel...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Gold, M E, Wood, K S, Byrns, R E, Fukuto, J, Ignarro, L J
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1990
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54128/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2162040/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.12.4430
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