Reduced local input to fast‐spiking interneurons in the somatosensory cortex in the GABA(A) γ2 R43Q mouse model of absence epilepsy

OBJECTIVE: Absence seizures in childhood absence epilepsy are initiated in the thalamocortical (TC) system. We investigated if these seizures result from altered development of the TC system before the appearance of seizures in mice containing a point mutation in γ‐aminobutyric acid A (GABA(A)) rece...

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Publicat a:Epilepsia
Autors principals: Currie, Stephen P., Luz, Liliana L., Booker, Sam A., Wyllie, David J. A., Kind, Peter C., Daw, Michael I.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
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Full‐length Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5412680/
https://ncbi.nlm.nih.gov/pubmed/28195311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.13693
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