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Brain Tumor Mutations Detected in Cerebral Spinal Fluid

BACKGROUND: Detecting tumor-derived cell-free DNA (cfDNA) in the blood of brain tumor patients is challenging, presumably owing to the blood–brain barrier. Cerebral spinal fluid (CSF) may serve as an alternative “liquid biopsy” of brain tumors by enabling measurement of circulating DNA within CSF to...

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Detalhes bibliográficos
Publicado no:Clin Chem
Main Authors: Pan, Wenying, Gu, Wei, Nagpal, Seema, Gephart, Melanie Hayden, Quake, Stephen R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5412506/
https://ncbi.nlm.nih.gov/pubmed/25605683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1373/clinchem.2014.235457
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