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Folic Acid Reduces Tau Phosphorylation by Regulating PP2A Methylation in Streptozotocin-Induced Diabetic Mice

High incidence rate of Alzheimer’s disease (AD) is observed in patients with type 2 diabetes. Aggregated β-amyloid (Aβ) and hyperphosphorylated tau are the hallmarks of AD. Hyperphosphorylated tau has been detected in diabetic animals as well as in diabetic patients. Folates mediate the transfer of...

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Detaylı Bibliyografya
Yayımlandı:Int J Mol Sci
Asıl Yazarlar: Zheng, Miaoyan, Zou, Chen, Li, Mengyue, Huang, Guowei, Gao, Yuxia, Liu, Huan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5412442/
https://ncbi.nlm.nih.gov/pubmed/28422052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18040861
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