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High Glucose Accelerates Cell Proliferation and Increases the Secretion and mRNA Expression of Osteopontin in Human Pancreatic Duct Epithelial Cells

Background: The incidence of pancreatic cancer is increasing year-by-year in Japan. Among the diseases that complicate pancreatic cancer, diabetes is the most common. Recently, it has become evident that patients suffering from diabetes and obesity show increased expression of osteopontin (OPN). The...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Ito, Miho, Makino, Naohiko, Matsuda, Akiko, Ikeda, Yushi, Kakizaki, Yasuharu, Saito, Yoshihiko, Ueno, Yoshiyuki, Kawata, Sumio
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5412391/
https://ncbi.nlm.nih.gov/pubmed/28417915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18040807
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