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Endogenously Expressed IL-4Rα Promotes the Malignant Phenotype of Human Pancreatic Cancer In Vitro and In Vivo

Exogenous interleukin-4 (IL-4) has been demonstrated to affect the growth of different human malignancies including pancreatic cancer cells. The aim of our study was to determine the role of endogenously expressed IL-4-receptor-α-chain (IL-4Rα) in pancreatic cancer cells. IL-4Rα-suppression was achi...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Traub, Benno, Sun, Lie, Ma, Yongsu, Xu, Pengfei, Lemke, Johannes, Paschke, Stephan, Henne-Bruns, Doris, Knippschild, Uwe, Kornmann, Marko
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5412302/
https://ncbi.nlm.nih.gov/pubmed/28350325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18040716
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