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The production method affects the efficacy of platelet derivatives to expand mesenchymal stromal cells in vitro
BACKGROUND: The use of fetal bovine serum (FBS) as a media supplement for the ex vivo expansion of bone-marrow derived mesenchymal stromal cells (BM-MSC) has been discouraged by regulatory agencies, due to the risk of transmitting zoonoses and to elicit immune reactions in the host once transplanted...
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Published in: | J Transl Med |
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Main Authors: | , , , , , , , , , , |
Format: | Artigo |
Language: | Inglês |
Published: |
BioMed Central
2017
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5412035/ https://ncbi.nlm.nih.gov/pubmed/28460641 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-017-1185-9 |
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