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The production method affects the efficacy of platelet derivatives to expand mesenchymal stromal cells in vitro

BACKGROUND: The use of fetal bovine serum (FBS) as a media supplement for the ex vivo expansion of bone-marrow derived mesenchymal stromal cells (BM-MSC) has been discouraged by regulatory agencies, due to the risk of transmitting zoonoses and to elicit immune reactions in the host once transplanted...

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Bibliographic Details
Published in:J Transl Med
Main Authors: Bernardi, Martina, Agostini, Francesco, Chieregato, Katia, Amati, Eliana, Durante, Cristina, Rassu, Mario, Ruggeri, Marco, Sella, Sabrina, Lombardi, Elisabetta, Mazzucato, Mario, Astori, Giuseppe
Format: Artigo
Language:Inglês
Published: BioMed Central 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5412035/
https://ncbi.nlm.nih.gov/pubmed/28460641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-017-1185-9
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