EPO-cyclosporine combination therapy reduced brain infarct area in rat after acute ischemic stroke: role of innate immune-inflammatory response, micro-RNAs and MAPK family signaling pathway

This study tested the hypothesis that erythropoietin (EPO) and cyclosporine (CsA) could effectively reduce brain infarct area (BIA) in rat after acute ischemic stroke (AIS) through regulating inflammation, oxidative stress, MAPK family signaling and microRNA (miR-223/miR-30a/miR-383). Adult male Spr...

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Vydáno v:Am J Transl Res
Hlavní autoři: Yuen, Chun-Man, Yeh, Kuo-Ho, Wallace, Christopher Glenn, Chen, Kuan-Hung, Lin, Hung-Sheng, Sung, Pei-Hsun, Chai, Han-Tan, Chen, Yung-Lung, Sun, Cheuk-Kwan, Chen, Chih-Hung, Kao, Gour-Shenq, Ko, Sheung-Fat, Yip, Hon-Kan
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2017
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5411915/
https://ncbi.nlm.nih.gov/pubmed/28469772
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