The mTOR-FAK mechanotransduction signaling axis for focal adhesion maturation and cell proliferation

Background: Mechanotransduction (MTD) is an important physiopathological signalling pathway associated with cardiovascular disease such as hypertension. Phosphorylation of focal adhesion kinase (FAK) is a MTD-sensing protein. This study tested the hypothesis that mTOR-FAK MTD signaling axis was cruc...

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Vydáno v:Am J Transl Res
Hlavní autoři: Lee, Fan-Yen, Zhen, Yen-Yi, Yuen, Chun-Man, Fan, Raymond, Chen, Yen-Ta, Sheu, Jiunn-Jye, Chen, Yi-Ling, Wang, Ching-Jen, Sun, Cheuk-Kwan, Yip, Hon-Kan
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2017
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5411911/
https://ncbi.nlm.nih.gov/pubmed/28469768
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