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Differential interactions of human choriogonadotropin and its antagonistic aglycosylated analog with their receptor.

Human choriogonadotropin (hCG) is a heterodimeric hormone consisting of an alpha subunit and a beta subunit. hCG and aglycosylated hCG (aghCG) have similar receptor binding affinities but differ in their ability to activate hormone-responsive adenylate cyclase. aghCG is an effective antagonist. The...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Ji, I, Ji, T H
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1990
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54117/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2349245/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.11.4396
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