Microglia activation and phagocytosis: relationship with aging and cognitive impairment in the rhesus monkey

While cognitive decline is observed in the normal aging monkey, neurons are not lost with age. Instead, frontal white matter is lost as myelin degenerates and both correlate with age-related cognitive decline. As age-related myelin damage increases, there should be an increase in clearance of damage...

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Pubblicato in:GeroScience
Autori principali: Shobin, Eli, Bowley, Michael P., Estrada, Larissa I., Heyworth, Nadine C., Orczykowski, Mary E., Eldridge, Sherri A., Calderazzo, Samantha M., Mortazavi, Farzad, Moore, Tara L., Rosene, Douglas L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer International Publishing 2017
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5411373/
https://ncbi.nlm.nih.gov/pubmed/28238188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-017-9965-y
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