Microglia activation and phagocytosis: relationship with aging and cognitive impairment in the rhesus monkey

While cognitive decline is observed in the normal aging monkey, neurons are not lost with age. Instead, frontal white matter is lost as myelin degenerates and both correlate with age-related cognitive decline. As age-related myelin damage increases, there should be an increase in clearance of damage...

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Detalhes bibliográficos
Publicado no:GeroScience
Main Authors: Shobin, Eli, Bowley, Michael P., Estrada, Larissa I., Heyworth, Nadine C., Orczykowski, Mary E., Eldridge, Sherri A., Calderazzo, Samantha M., Mortazavi, Farzad, Moore, Tara L., Rosene, Douglas L.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2017
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5411373/
https://ncbi.nlm.nih.gov/pubmed/28238188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-017-9965-y
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