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Using Bacterial Genomes and Essential Genes for the Development of New Antibiotics

The shrinking antibiotic development pipeline together with the global increase in antibiotic resistant infections requires that new molecules with antimicrobial activity are developed. Traditional empirical screening approaches of natural and non-natural compounds have identified the majority of an...

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Detalhes bibliográficos
Publicado no:Biochem Pharmacol
Main Authors: Fields, Francisco R., Lee, Shaun W., McConnell, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5411290/
https://ncbi.nlm.nih.gov/pubmed/27940263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2016.12.002
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