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Hypoxia-induced HIF1α targets in melanocytes reveal a molecular profile associated with poor melanoma prognosis

Hypoxia and HIF1α signaling direct tissue-specific gene responses regulating tumor progression, invasion and metastasis. By integrating HIF1α knockdown and hypoxia-induced gene expression changes, this study identifies a melanocyte-specific, HIF1α-dependent/hypoxia-responsive gene expression signatu...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Pigment Cell Melanoma Res
Prif Awduron: Loftus, Stacie K., Baxter, Laura L., Cronin, Julia C., Fufa, Temesgen D., Pavan, William J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5411287/
https://ncbi.nlm.nih.gov/pubmed/28168807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pcmr.12579
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