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Localization and in-Vivo Characterization of Thapsia garganica CYP76AE2 Indicates a Role in Thapsigargin Biosynthesis

The Mediterranean plant Thapsia garganica (dicot, Apiaceae), also known as deadly carrot, produces the highly toxic compound thapsigargin. This compound is a potent inhibitor of the sarcoplasmic-endoplasmic reticulum Ca(2+)-ATPase calcium pump in mammals and is of industrial importance as the active...

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Détails bibliographiques
Publié dans:Plant Physiol
Auteurs principaux: Andersen, Trine Bundgaard, Martinez-Swatson, Karen Agatha, Rasmussen, Silas Anselm, Boughton, Berin Alain, Jørgensen, Kirsten, Andersen-Ranberg, Johan, Nyberg, Nils, Christensen, Søren Brøgger, Simonsen, Henrik Toft
Format: Artigo
Langue:Inglês
Publié: American Society of Plant Biologists 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5411132/
https://ncbi.nlm.nih.gov/pubmed/28275147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1104/pp.16.00055
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