Pediatric necrotizing myopathy associated with anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase antibodies

Objective. Antibodies against 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) have recently been associated with immune-mediated necrotizing myopathy, especially in patients with statin exposure. As the data are very limited concerning phenotypes and treatment in paediatric patients, we aime...

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Bibliographic Details
Published in:Rheumatology (Oxford)
Main Authors: Liang, Wen-Chen, Uruha, Akinori, Suzuki, Shigeaki, Murakami, Nobuyuki, Takeshita, Eri, Chen, Wan-Zi, Jong, Yuh-Jyh, Endo, Yukari, Komaki, Hirofumi, Fujii, Tatsuya, Kawano, Yutaka, Mori-Yoshimura, Madoka, Oya, Yasushi, Xi, Jianying, Zhu, Wenhua, Zhao, Chongbo, Watanabe, Yurika, Ikemoto, Keisuke, Nishikawa, Atsuko, Hamanaka, Kohei, Mitsuhashi, Satomi, Suzuki, Norihiro, Nishino, Ichizo
Format: Artigo
Language:Inglês
Published: Oxford University Press 2017
Subjects:
Basic and Translational Science
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5410926/
https://ncbi.nlm.nih.gov/pubmed/27818386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/rheumatology/kew386
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