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Molecular basis for the interaction between Integrator subunits IntS9 and IntS11 and its functional importance

The metazoan Integrator complex (INT) has important functions in the 3′-end processing of noncoding RNAs, including the uridine-rich small nuclear RNA (UsnRNA) and enhancer RNA (eRNA), and in the transcription of coding genes by RNA polymerase II. The INT contains at least 14 subunits, but its molec...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Wu, Yixuan, Albrecht, Todd R., Baillat, David, Wagner, Eric J., Tong, Liang
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5410846/
https://ncbi.nlm.nih.gov/pubmed/28396433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1616605114
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