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Structure of a DNA glycosylase that unhooks interstrand cross-links

DNA glycosylases are important editing enzymes that protect genomic stability by excising chemically modified nucleobases that alter normal DNA metabolism. These enzymes have been known only to initiate base excision repair of small adducts by extrusion from the DNA helix. However, recent reports ha...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Mullins, Elwood A., Warren, Garrett M., Bradley, Noah P., Eichman, Brandt F.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5410837/
https://ncbi.nlm.nih.gov/pubmed/28396405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1703066114
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