Extracellular Signal-Regulated Kinase Signaling in CD4-Expressing Cells Inhibits Osteochondromas

Defects in cartilage homeostasis can give rise to various skeletal disorders including osteochondromas. Osteochondromas are benign bone tumors caused by excess accumulation of chondrocytes, the main cell type of cartilage. The extracellular signal-regulated kinase (ERK) pathway is a major signaling...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Wehenkel, Marie, Corr, Maripat, Guy, Clifford S., Edwards, Benjamin A., Castellaw, Ashley H., Calabrese, Christopher, Pagès, Gilles, Pouysségur, Jacques, Vogel, Peter, McGargill, Maureen A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5410564/
https://ncbi.nlm.nih.gov/pubmed/28507546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00482
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