The TERT promoter mutation incidence is modified by germline TERT rs2736098 and rs2736100 polymorphisms in hepatocellular carcinoma

Telomerase activation via induction of the catalytic component telomerase reverse transcriptase (TERT) plays essential roles in malignant transformation. TERT promoter-activating mutations were recently identified as a novel mechanism to activate telomerase in hepatocellular carcinoma (HCC) and many...

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Pubblicato in:Oncotarget
Autori principali: Yuan, Xiaotian, Cheng, Guanghui, Yu, Jingya, Zheng, Shunzhen, Sun, Chao, Sun, Qing, Li, Kailin, Lin, Zhaomin, Liu, Tiantian, Li, Ping, Xu, Yiteng, Kong, Feng, Bjorkholm, Magnus, Xu, Dawei
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5410290/
https://ncbi.nlm.nih.gov/pubmed/28416747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15498
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