The TERT promoter mutation incidence is modified by germline TERT rs2736098 and rs2736100 polymorphisms in hepatocellular carcinoma

Telomerase activation via induction of the catalytic component telomerase reverse transcriptase (TERT) plays essential roles in malignant transformation. TERT promoter-activating mutations were recently identified as a novel mechanism to activate telomerase in hepatocellular carcinoma (HCC) and many...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Yuan, Xiaotian, Cheng, Guanghui, Yu, Jingya, Zheng, Shunzhen, Sun, Chao, Sun, Qing, Li, Kailin, Lin, Zhaomin, Liu, Tiantian, Li, Ping, Xu, Yiteng, Kong, Feng, Bjorkholm, Magnus, Xu, Dawei
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2017
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5410290/
https://ncbi.nlm.nih.gov/pubmed/28416747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15498
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