Overlooked FANCD2 variant encodes a promising, portent tumor suppressor, and alternative polyadenylation contributes to its expression

Fanconi Anemia (FA) complementation group D2 protein (FANCD2) is the center of the FA tumor suppressor pathway, which has become an important field of investigation in human aging and cancer. Here we report an overlooked central player in the FA pathway, FANCD2 variant 2 (FANCD2-V2), which appears t...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Han, Bing, Shen, Yihang, Zhang, Piyan, Jayabal, Panneerselvam, Che, Raymond, Zhang, Jun, Yu, Herbert, Fei, Peiwen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5410239/
https://ncbi.nlm.nih.gov/pubmed/28157704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14989
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