Porcine reproductive and respiratory syndrome virus 3C protease cleaves the mitochondrial antiviral signalling complex to antagonize IFN-β expression

Porcine reproductive and respiratory syndrome, a highly infectious disease caused by porcine reproductive and respiratory syndrome virus (PRRSV), has developed various strategies to evade the host innate immune response, including the suppression of type I IFN activation. The mitochondrial antiviral...

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Publicat a:J Gen Virol
Autors principals: Dong, Jianming, Xu, Shangen, Wang, Jing, Luo, Rui, Wang, Dang, Xiao, Shaobo, Fang, Liurong, Chen, Huanchun, Jiang, Yunbo
Format: Artigo
Idioma:Inglês
Publicat: Microbiology Society 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5410108/
https://ncbi.nlm.nih.gov/pubmed/26253126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jgv.0.000257
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