Binary agonist surface patterns prime platelets for downstream adhesion in flowing whole blood

As platelets encounter damaged vessels or biomaterials, they interact with a complex milieu of surface-bound agonists, from exposed subendothelium to adsorbed plasma proteins. It has been shown that an upstream, surface-immobilized agonist is capable of priming platelets for enhanced adhesion downst...

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Veröffentlicht in:Biointerphases
Hauptverfasser: Eichinger, Colin D., Hlady, Vladimir
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Vacuum Society 2017
Schlagworte:
In Focus: Biointerface Science and Engineered Biomaterials - An Issue in Honor of Professor Buddy Ratner’s 70th Birthday
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5409849/
https://ncbi.nlm.nih.gov/pubmed/28454486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1116/1.4982596
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