Clonal architecture of CXCR4 WHIM-like mutations in Waldenström Macroglobulinaemia

CXCR4(WHIM) somatic mutations are distinctive to Waldenstrom Macroglobulinaemia (WM), and impact disease presentation and treatment outcome. The clonal architecture of CXCR4(WHIM) mutations remains to be delineated. We developed highly sensitive allele-specific polymerase chain reaction(AS-PCR) assa...

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Détails bibliographiques
Publié dans:Br J Haematol
Auteurs principaux: Xu, Lian, Hunter, Zachary R., Tsakmaklis, Nicholas, Cao, Yang, Yang, Guang, Chen, Jie, Liu, Xia, Kanan, Sandra, Castillo, Jorge J., Tai, Yu-Tzu, Zehnder, James L., Brown, Jennifer R., Carrasco, Ruben D., Advani, Ranjana, Sabile, Jean M., Argyropoulos, Kimon, Palomba, M. Lia, Morra, Enrica, Trojani, Alessandra, Greco, Antonino, Tedeschi, Alessandra, Varettoni, Marzia, Arcaini, Luca, Munshi, Nikhil M., Anderson, Kenneth C., Treo, Steven P.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5409813/
https://ncbi.nlm.nih.gov/pubmed/26659815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bjh.13897
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