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Homocysteine Induces Hepatic Steatosis Involving ER Stress Response in High Methionine Diet-Fed Mice

Elevated circulating homocysteine (Hcy) has been proposed to be associated with non-alcoholic fatty liver disease (NAFLD). It is also reported that Hcy causes protein misfolding in the endoplasmic reticulum (ER). In this study, we used a high methionine diet (HMD)-fed mouse model and cultured primar...

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Detalhes bibliográficos
Publicado no:Nutrients
Main Authors: Ai, Yanbiao, Sun, Zhenzhen, Peng, Chuan, Liu, Lingli, Xiao, Xiaoqiu, Li, Jibin
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5409685/
https://ncbi.nlm.nih.gov/pubmed/28368295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu9040346
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