Multiple roles of filopodial dynamics in particle capture and phagocytosis and phenotypes of Cdc42 and Myo10 deletion

Macrophage filopodia, finger-like membrane protrusions, were first implicated in phagocytosis more than 100 years ago, but little is still known about the involvement of these actin-dependent structures in particle clearance. Using spinning disk confocal microscopy to image filopodial dynamics in mo...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Horsthemke, Markus, Bachg, Anne C., Groll, Katharina, Moyzio, Sven, Müther, Barbara, Hemkemeyer, Sandra A., Wedlich-Söldner, Roland, Sixt, Michael, Tacke, Sebastian, Bähler, Martin, Hanley, Peter J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2017
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5409491/
https://ncbi.nlm.nih.gov/pubmed/28289096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.766923
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