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Surface Presentation of Functional Peptides in Solution Determines Cell Internalization Efficiency of TAT Conjugated Nanoparticles

Functionalizing nanoparticles with cell-penetrating peptides is a popular choice for cellular delivery. We investigated the effects of TAT peptide concentration and arrangement in solution on functionalized nanoparticles’ efficacy for membrane permeation. We found that cell internalization correlate...

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Detalhes bibliográficos
Publicado no:Nano Lett
Main Authors: Todorova, Nevena, Chiappini, Ciro, Mager, Morgan, Simona, Benjamin, Patel, Imran I., Stevens, Molly M., Yarovsky, Irene
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5408925/
https://ncbi.nlm.nih.gov/pubmed/25157643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nl5021848
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