Development of Clostridium difficile R20291ΔPaLoc model strains and in vitro methodologies reveals CdtR is required for the production of CDT to cytotoxic levels

Assessing the regulation of Clostridium difficile transferase (CDT), is complicated by the presence of a Pathogenicity locus (PaLoc) which encodes Toxins A and B. Here we developed R20291ΔPaLoc model strains and cell-based assays to quantify CDT-mediated virulence. Their application demonstrated tha...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Anaerobe
मुख्य लेखकों: Bilverstone, T.W., Kinsmore, N.L., Minton, N.P., Kuehne, S.A.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Academic Press 2017
विषय:
Short Communication
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5408908/
https://ncbi.nlm.nih.gov/pubmed/28108389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.anaerobe.2017.01.009
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