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switchde: inference of switch-like differential expression along single-cell trajectories

MOTIVATION: Pseudotime analyses of single-cell RNA-seq data have become increasingly common. Typically, a latent trajectory corresponding to a biological process of interest—such as differentiation or cell cycle—is discovered. However, relatively little attention has been paid to modelling the diffe...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Campbell, Kieran R, Yau, Christopher
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5408844/
https://ncbi.nlm.nih.gov/pubmed/28011787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw798
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