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Optimizing ChIP-seq peak detectors using visual labels and supervised machine learning

MOTIVATION: Many peak detection algorithms have been proposed for ChIP-seq data analysis, but it is not obvious which algorithm and what parameters are optimal for any given dataset. In contrast, regions with and without obvious peaks can be easily labeled by visual inspection of aligned read counts...

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Detaylı Bibliyografya
Yayımlandı:Bioinformatics
Asıl Yazarlar: Hocking, Toby Dylan, Goerner-Potvin, Patricia, Morin, Andreanne, Shao, Xiaojian, Pastinen, Tomi, Bourque, Guillaume
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5408812/
https://ncbi.nlm.nih.gov/pubmed/27797775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw672
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