Engineering bacterial thiosulfate and tetrathionate sensors for detecting gut inflammation

There is a groundswell of interest in using genetically engineered sensor bacteria to study gut microbiota pathways, and diagnose or treat associated diseases. Here, we computationally identify the first biological thiosulfate sensor and an improved tetrathionate sensor, both two‐component systems f...

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Bibliographic Details
Published in:Mol Syst Biol
Main Authors: Daeffler, Kristina N‐M, Galley, Jeffrey D, Sheth, Ravi U, Ortiz‐Velez, Laura C, Bibb, Christopher O, Shroyer, Noah F, Britton, Robert A, Tabor, Jeffrey J
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2017
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5408782/
https://ncbi.nlm.nih.gov/pubmed/28373240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20167416
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