ABCG1 regulates pulmonary surfactant metabolism in mice and men

Idiopathic pulmonary alveolar proteinosis (PAP) is a rare lung disease characterized by accumulation of surfactant. Surfactant synthesis and secretion are restricted to epithelial type 2 (T2) pneumocytes (also called T2 cells). Clearance of surfactant is dependent upon T2 cells and macrophages. ABCG...

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Bibliografiske detaljer
Udgivet i:J Lipid Res
Main Authors: de Aguiar Vallim, Thomas Q., Lee, Elinor, Merriott, David J., Goulbourne, Christopher N., Cheng, Joan, Cheng, Angela, Gonen, Ayelet, Allen, Ryan M., Palladino, Elisa N. D., Ford, David A., Wang, Tisha, Baldán, Ángel, Tarling, Elizabeth J.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2017
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5408613/
https://ncbi.nlm.nih.gov/pubmed/28264879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M075101
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