A Recombinant Vesicular Stomatitis Virus Ebola Vaccine

BACKGROUND: The worst Ebola virus disease (EVD) outbreak in history has resulted in more than 28,000 cases and 11,000 deaths. We present the final results of two phase 1 trials of an attenuated, replication-competent, recombinant vesicular stomatitis virus (rVSV)–based vaccine candidate designed to...

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Publicat a:N Engl J Med
Autors principals: Regules, J.A., Beigel, J.H., Paolino, K.M., Voell, J., Castellano, A.R., Hu, Z., Muñoz, P., Moon, J.E., Ruck, R.C., Bennett, J.W., Twomey, P.S., Gutiérrez, R.L., Remich, S.A., Hack, H.R., Wisniewski, M.L., Josleyn, M.D., Kwilas, S.A., Van Deusen, N., Mbaya, O.T., Zhou, Y., Stanley, D.A., Jing, W., Smith, K.S., Shi, M., Ledgerwood, J.E., Graham, B.S., Sullivan, N.J., Jagodzinski, L.L., Peel, S.A., Alimonti, J.B., Hooper, J.W., Silvera, P.M., Martin, B.K., Monath, T.P., Ramsey, W.J., Link, C.J., Lane, H.C., Michael, N.L., Davey, R.T., Thomas, S.J.
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5408576/
https://ncbi.nlm.nih.gov/pubmed/25830322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1414216
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